The Epigenetics Revolution (51 page)
Read The Epigenetics Revolution Online
Authors: Nessa Carey
Tags: #Science/Life Sciences/Genetics and Genomics
Merck
messenger RNA
see
mRNA
see
mRNA
methyl donors
5-methylcytosine
methylcytosine
mice
age-related DNA methylation changes
agouti
Avy
Avyla
B6 strain
BALB strain
body weight
Dnmt1
mutant
mutant
early-life stress model
Grb10
mutant
mutant
kinked tail (Axin-fused)
with
MeCP2
mutation
MeCP2
mutation
memory
resveratol-treated
Sirt6
knockout
knockout
social defeat model
sucrose-preference test
microRNAs
see
miRNAs
see
miRNAs
miR-15a
RNA
RNA
miR-16–1
RNA
RNA
miR-17–92
cluster
cluster
miR-189 RNA
miRNAs
in cancer
in cellular differentiation control
in pluripotency control
misery memoirs
mitochondria
MLL2
MLL2
gene
gene
MMR vaccine
molecular memory
molecular weight
moles
Monod, Jacques
Moore, Gudrun
mouse chromosome 7
mouse chromosome 11
mouse chromosome 12
mouse chromosome 15
mouse chromosome 17
mouse embryonic fibroblasts (MEFs)
Mousetrap
MPSII
mRNA
3´ UTR region
5´ UTR region
destruction
detection
discovery
mucopolysacchardidosis II (MPSII)
multiple myeloma
multiple sclerosis
muscle
muscle cells
muscle wasting
Mustela ermine
mutagens
mutations
rates
somatic
myelodysplastic syndrome
myostatin
MZ twins
see
identical twins
see
identical twins
Nanog
National Cancer Institute
ncRNAs
abnormal production
defects in
editing
and gene expression increase/decrease
long
short
see also
miRNAs
miRNAs
negative feedback loops
nematode
see Caenorhabditis elegans
see Caenorhabditis elegans
neomycin
neomycin resistance (
neoR
) gene
neoR
) gene
neural stem cells
neuro-epigenetics
neuronal cells
neurons
as terminally differentiated
neurotransmitters
neurotrophic factors
non-coding RNA
see
ncRNA
see
ncRNA
non-small cell lung cancer
Novartis
nucleic acids, drugs around
nucleosomes
nucleus
nucleus accumbens
nurse bees
nutrition
in honeybees
see also
calorie restriction; malnutrition
calorie restriction; malnutrition
obesity, epigenetics of
Oct4
Oct4
gene
gene
oestrogen
Överkalix
painted lady caterpillar/butterfly
pancreas
paradigm shifts
parent-of-origin effects
parthenogenesis
patents
Pelzer, Dave
penicillin
Pfizer
phantom limb syndrome
pharmaceutical companies
phenotypes
phenyl butyrate
PHF8
PHF8
gene
gene
Philadelphia chromosome
phosphate
photosynthesis
Piraha tribe
pituitary
PIWI proteins
PIWI RNAs
placenta
imprinting in
placental mammals
Planck, Max
plants
differences from animals
sexual reproduction
similarities with animals
specialised cells
vernalisation
pleasure
pluripotency
pluripotency genes
pluripotent cells, creation
poised state
polio
pollen
polyps
post-transcriptional gene silencing
pouch
Prader-Willi syndrome (PWS)
PRC2
primordial germ cells
promoters
pronuclei
prostate cancer
proteins
evolution
importance
regulation
see also
histones
histones
proto-oncogenes
pseudoautosomal regions
psyche
psychological damage
quality of life
queen bees
activities
brains
physical form
Rana pipiens
random variation
rats
age-related DNA methylation changes
folic acid in
mothering skills
Sprague-Dawley
red blood cells
Regulus Therapeutics
repetitive DNA
replication complex
reprogramming
resveratol
retrotransposons
IAP
in plants
Rett syndrome
reward
rheumatoid arthritis
ribonucleic acid
see
RNA
see
RNA
ribosomal RNA
see
rRNA
see
rRNA
ribosomes
Richon, Victoria
Rifkind, Richard
RNA
see also
mRNA; ncRNA
mRNA; ncRNA
Roberts, Richard
Robinson, Gene
Roche
romidepsin
royal jelly
rRNA
Rubinstein-Taybi syndrome
S-adenosyl methionine (SAM)
Saccharomyces cerevisiae see
yeast
yeast
SAHA
as cancer controller
and memory
side-effects
structure
SAM
Sanofi-Aventis
satellite cells
schizophrenia
concordance rates
maternal malnutrition and
SCNT
SDG27
gene
gene
seeds
seizures
selective serotonin re-uptake inhibitors (SSRIs)
selfish DNA
senescence
serotonin
sex chromosomes
abnormalities in number
see also
X chromosome; Y chromosome
X chromosome; Y chromosome
sex determination
Sharp, Phillip
sheep, Texel
Shiekhattar, Ramin
SHOX
SHOX
gene
gene
sickle cell disease
Silver-Russell syndrome
Sinclair, David
Sir2
Sirna Theraputics
siRNAs
SIRT1
SIRT2
SIRT3
SIRT4
SIRT5
SIRT6
SIRT6
gene
gene
SIRT7
Sirtris Pharmaceuticals
sirtuins
skeletal muscle
SLITRK1
gene
gene
slow growth period (SGP)
small interfering RNAs
see
siRNAs
see
siRNAs
Smith, Austin
SNORD116
gene
gene
Sobel, Davor
SOC1
gene
gene
social defeat
sodium butyrate
sodium valproate
Solter, Davor
somatic cell nuclear transfer (SCNT)
somatic cells
somatic mutations
soul
Sox2
Sox2
gene
gene
sperm
epigenome
nucleus
spina bifida
splicing
SRY
SRY
gene
gene
SSRIs
Stellwagen, Robert
stem cells
in cancer
pluripotent
stick insects
stoats
stochastic processes
stop codons
stress
stroke
The Structure of Scientific Revolutions
sub-telomeric regions
suberoylanilide hydroxamic acid
see
SAHA
see
SAHA
sucrose-preference test
sugar metabolism
suicide
sulphoraphane
Sulston, John
Surani, Azim
as Nobel Prize candidate
swearing
sweating
syncytial tissue
systemic lupus erythematosus
Szent-Gyorgyi, Albert
Szostak, Jack
T cell lymphomas
T cells
Takahashi, Kazutoshi
TARBP2
TARBP2
gene
gene
Tasmanian devil
Taylor, Shirley
telomerase
telomeres
termites
testes, formation
testosterone
TEs
TET1
TET2
TET3
Texel sheep
therapeutic cloning
thymine (T)
tics
tissue regeneration
toad eggs
toads, midwife
totipotency
Tourette’s syndrome
transcription
transcriptional noise
transcriptional repressors
transfer RNA
see
tRNA
see
tRNA
transgenerational inheritance
transposable elements (TEs)
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