Authors: Mary A. Williamson Mt(ascp) Phd,L. Michael Snyder Md
Because of the extreme rarity of some lymphomas (B- or T-cell lymphoblastic leukemia/lymphoma, primary cutaneous follicle center lymphoma, aggressive NK cell leukemia, angioimmunoblastic T-cell lymphoma, peripheral T-cell lymphoma [unspecified], hepatosplenic T-cell lymphoma, T-cell lymphoma, nasal type, adult T-cell leukemia/lymphoma, anaplastic large cell lymphoma, ALK positive or negative, enteropathy-associated intestinal T-cell lymphoma, subcutaneous panniculitis-like T-cell lymphoma, primary cutaneous gammadelta T-cell lymphoma, primary cutaneous CD30
+
T-cell lymphoproliferative disease, lymphomatoid papulosis, and primary cutaneous anaplastic large cell lymphoma) and space constraints, these entities will not be included. The reader is referred to the WHO classification manual or specialty hematopathology textbooks.
The following types of non-Hodgkin lymphoma and diagnostic approaches are described in subsequent sections:
Diffuse large cell (see p. 422)
Follicular (see p. 423)
Mantle zone (see p. 424)
Marginal zone (see p. 425)
Burkitt (see p. 420)
Cutaneous (see p. 421)
Lymphoplasmacytic (see p. 427)
Posttransplantation (see p. 427)
Common Laboratory Findings (Type-Specific Findings Will Be Presented With Each Lymphoma Chapter)
Abnormalities of humoral immunity: hypogammaglobulinemia and occasionally monoclonal gammopathies
Autoimmune hemolytic anemia and/or thrombocytopenia