Read The Rise and Fall of Modern Medicine Online
Authors: James Le Fanu
9
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19
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Matthew Bacchetta, Wilson Ko
et al
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, 2003, Vol. 75, pp. 1215â20. See also Padmini Varadarajan, Nikhil Kapoor and Ramesh Bansal, âSurvival in Elderly Patients with a Severe Aortic Stenosis is Dramatically Improved by Aortic Valve Replacement'
, European Journal of Cardio-Thoracic Surgery
, 2006, Vol. 30, pp. 722â27. See also J. Unsworth-White, âCardiac Surgery for the Elderly: A Surgeon's Perspective',
Heart
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20
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et al
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21
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1
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Kevin Davies,
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(Baltimore, MD: John Hopkins University Press,
2001). See also John Sulston and Georgina Ferry,
The Common Thread: A History of Science, Politics, Ethics and the Human Genome
(Bantam Press, 2002); Nicholas Wade,
Life Script
(Simon & Schuster, 2001).
2
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International Human Genome Sequencing Consortium, âInitial Sequencing and Analysis of the Human Genome',
Nature
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Science
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3
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Francis Collins and Victor McKusick, âImplications of the Human Genome Project for Medical Science',
Chalmer
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4
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J. Craig Venter, âMultiple Personal Genomes Await',
Nature
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5
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âScience in the Petabyte Era',
Nature
, 2008, Vol. 455, p. VII.
6
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Francis Collins, âHas the Revolution Arrived?',
Nature
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7
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Erika Check Hayden, âLife is Complicated',
Nature
, 2010, Vol. 464, pp. 664â7.
8
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Phillip Ball, âBursting the Genomics Bubble',
Nature
, 2010, doi: 10.1038/news.2010.155.
9
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Editorial, âThe Human Genome Project: Ten Years Later',
The Lancet
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10
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Nicholas Wade, âA Decade Later, Genetic Map Yields Few New Cures',
New York Times
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11
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Steve Jones, âOne Gene Will Not Reveal All Life's Secrets',
Daily Telegraph
, 21 April 2009.
12
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Brendan Maher, âThe Case of the Missing Heritability',
Nature
, 2008, Vol. 456, pp. 18â21.
13
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Peter Donnelly, âProgress and Challenges in Genome-Wide Association Studies in Humans',
Nature
, 2008, Vol. 456, pp. 728â34. See also Teri Manolio, âGenome Wide Association Studies and Assessment of the Risk of Disease',
NEJM
, 2010, Vol. 363, pp. 136â76.
14
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Anne Bocock, âGuilt by Association',
Nature
, 2007, Vol. 447, pp. 645â9.
15
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Teri Manolio, âCohort Studies and the Genetics of Complex Disease',
Nature Genetics
, 2009, Vol. 41, pp. 5â10.
16
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Jeffrey Barrett, Sarah Hansoul and Dan Nicolae, âGenome-Wide Association Defines more than Thirty Distinct Susceptibility Loci
for Crohns Disease',
Nature Genetics
, 2008, Vol. 40, pp. 955â61.
17
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D. F. Gutbjartsson, G. B. Walters and G. Thorleifsson, âMany Sequence Variance Affecting Diversity of Adult Human Height',
Nature Genetics
, 2008, Vol. 40, pp. 609â15. See also Michael Weedon and Timothy Frayling, âReaching New Heights: Insights into the Genetics of Human Stature',
Trends in Genetics
, pp. 695â700.
18
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Steve Jones, âOne Gene Will Not Reveal All Life's Secrets',
Daily Telegraph
, 21 April 2009.
19
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Amy McGuire, Mildred Chow
et al
., âThe Future of Personal Genomics',
Science
, 2007, Vol. 317, p. 1687.
20
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Emmanouil Dermitzakis and Andrew Clark, âLife After GWA Studies',
Science
, 2009, Vol. 326, pp. 239â40.
21
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22
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et al
., âThe Gene Number Dilemma: Direct Evidence for at Least 19,000 Protein-encoding Genes in C. elegans, and Implications for the Human Genome',
Nature Genetics
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23
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Sean Carroll,
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(Weidenfield and Nicolson, 2005).
24
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James Le Fanu,
Why Us?: How Science Rediscovered the Mystery of Ourselves
(HarperCollins, 2009).
1
.
Jerome Kassirer,
On the Take
(OUP, 2004); Melody Petersen,
Our Daily Meds: How the Pharmaceutical Companies Transformed Themselves into Slick Marketing Machines and Hooked the Nation on Prescription Drugs
(New York: Picador, 2008); John Abramson,
Overdosed America
(New York: Harper Perennial, 2008); Shannon Brownlee,
Overtreated: How Too Much Medicine is Making Us Sicker and Poorer
(Bloomsbury, 2008); Ray Moynihan and Alan Cassels,
Selling Sickness: How the World's Biggest Pharmaceutical Companies Are Turning Us All into Patients
(New York: Nation Books, 2005).
2
.
Marcia Angell,
The Truth about the Drug Companies
,
How They Deceive Us and What to Do About it
. (New York: Random House, 2004).
3
.
Ibid.
4
.
Ray Moynihan and Alan Cassells,
Selling Sickness
(New York: Nation Books, 2005).
5
.
Melody Petersen,
Our Daily Meds
(New York: Picadfor, 2008).
6
.
Vince Parry, âThe Art of Branding a Condition',
Medical Marketing and Media
, 2003, Vol. 38, pp. 43â8.
7
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Ray Moynihan, Iona Heath and David Henry, âSelling Sickness: The Pharmaceutical Industry and Disease Mongering',
BMJ
, 2002, Vol. 324, pp. 886â90.
8
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Marcia Angell,
The Truth About the Drug Companies
(New York: Random House, 2004).
9
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et al
., âWhy Olanzapine Beats Risperidone, Risperidone Beats Quetiapine, and Quetiapine Beats Olanzapine',
American Journal of Psychiatry
, 2006, Vol. 163, pp. 185â294.
10
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Marcia Angell, âIs Academic Medicine for Sale?',
NEJM
, 2000, Vol. 342, pp. 1516â18.
11
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Martin Keller, James McCullough, Daniel Kline
et al
., âA Comparison of Nefazodone, the Cognitive Behavioural-Analysis System of Psychotherapy, and Their Combination for the Treatment of Chronic Depression',
NEJM
, 2000, Vol. 342, pp. 1462â71.
12
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Thomas Bodenheimer, âUneasy Alliance: Clinical Investigators in the Pharmaceutical Industry',
BMJ
, 2000, Vol. 342, pp. 1539â41.
13
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Irvine Kirsch,
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(Bodley Head, 2009).
14
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William Appleton,
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(New York: Penguin, 2000).
15
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R. Kessler, K. McGonagle, S. Zhao
et al
., âLifetime and Twelve Month Prevalence of DSM â III â R Psychiatric Disorders in the United States. Results from the National Comorbility Survey',
Archives of General Psychiatry
, 1994, Vol. 51, pp. 8â19.
16
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Alisdair Santhouse, âThe Person in the Patient',
BMJ
, 428:a2262.
17
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Quoted in Jackie Law,
Big Pharma: How the World's Biggest Drug Companies Control Illness
(Constable, 2006).
18
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Cheryll Barron, âBig Pharma Snared by Net',
Observer
, 26 September 2004.
19
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Jackie Law,
Big Pharma: How the World's Biggest Drug Companies Control Illness
(Constable, 2006).
20
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Irvine Kirsch, 2009,
The Emperor's New Drugs
(Bodley Head, 2009).
21
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Dr Malcolm Kendrick,
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(John Blake, 2007).
22
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The Lancet
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23
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JAMA
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24
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D. Ricks and R. Raben, âCholesterol Guidelines, Drugs Panelist Links Under Fire',
Newsday
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25
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J. Abramson and J. M. Wright, âAre Lipid Lowering Guide Lines Evidence-Based?',
The Lancet
, 2007, Vol. 369, pp. 168â9.
26
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BMJ
, 2006, Vol. 232, pp. 1330â2.
27
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D. S. King, A. J. Wilburn, M. R. Wofford
et al
., âCognitive Impairment Associated with Atorvastatin and Simvastatin',
Pharmacotherapy
, 2003, Vol. 23, pp. 1623â7.
28
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et al
., âStatin-Associated Memory Loss: Analysis of Sixty Case Reports and Review of the Literature',
Pharmacotherapy
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29
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Christopher Hudson, âThe Wonder Drug That Stole My Memory',
Daily Telegraph
, 12th March 2009.
30
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et al
., âStatins and Risk of Polyneuropathy: A Case Controlled Study',
Neurology
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31
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BMJ
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32
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et al
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Archives of Internal Medicine
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