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Authors: JJ Virgin

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Food sensitivities keep your immune system fired up on a chronic basis.

Here’s another way in which allergic responses differ from sensitive ones: allergic responses are acute, whereas sensitivity responses are chronic. In other words, an allergy is a specific response: your immune system is activated, it flares up, it sends out its aggressive battery of IgE antibodies, and hopefully,
it calms down. Food sensitivities, by contrast, can keep your immune system fired up on a chronic basis because you keep consuming the foods that set them off. If yogurt, eggs, soy milk and whole-wheat bread are a frequent part of your diet—and especially if you’re eating them every day—your system is overwhelmed with problem foods, and your immune system never really calms down. This creates a number of problems, particularly inflammation, as I’ll explain a bit later. But first, let’s play food detective. Here are the typical symptoms of food sensitivity. Do any of them sound familiar to you?

  • Digestive trouble, such as bloating, gas, constipation or diarrhea
  • Sleep issues, such as fatigue, insomnia or waking in the middle of the night
  • Congestion, sneezing and coughing
  • Muscle aches and joint pain
  • Dark circles under your eyes
  • Dull, lifeless hair
  • Skin problems, including acne and rosacea
  • Mood problems, such as lack of focus, brain fog, depression, anxiety or irritability
  • Poor or unsteady energy
  • Weight gain
  • Premature aging

If you’re struggling with any of these symptoms, you are almost certainly struggling with food sensitivities and perhaps with other types of food intolerance as well.

Food sensitivity is incredibly common. It affects at least 75 percent of us and is a major factor in weight gain and weight retention. Again, the good news is that the Virgin Diet will help you cope with your food
sensitivities, first by pulling problem foods from your diet and then by healing your system so you might eventually be able to tolerate some of those foods.

FOOD REACTIONS

When you load your body up with too many carbs or too much sugar, you’re setting yourself up for blood sugar spikes and crashes. This in turn messes with your
insulin response
—your body’s attempt to move sugar out of your blood and into your cells. Your insulin response works best when your blood sugar levels are nice and steady and in the ideal range. The Virgin Diet supports this process and helps you avoid food reactions by having you eat ideal amounts of clean, lean protein; healthy fats; nonstarchy veggies; and high-fiber, low-glycemic carbs every 4 to 6 hours. Yes, pulling the top 7 high-FI foods is important, but so is the timing of your meals and the combinations of foods you eat. Consuming something sweet or high-carb—a piece of cake, a handful of dried fruit or even a glass of orange juice—causes your blood sugar to spike and messes with your insulin response. As you’ll see in
Chapter 7
, artificial sweeteners can also create adverse reactions. Anything that interferes with blood sugar and insulin response disrupts your stress hormones—all of which makes you more likely to gain and retain weight.

INFLAMMATION: FANNING THE FLAMES

Food intolerance produces a host of symptoms, which is bad enough. But it also causes a number of interrelated problems, each of which makes
all the others worse. One of those problems is
inflammation,
a major cause of weight gain and weight-loss resistance.

Ironically, inflammation is a necessary by-product of any intense immune response—that is, it’s supposed to help your system heal. When your body is invaded by a toxin, bacteria or a virus or traumatized by a wound, your immune system swiftly triggers a cascade of healing and protective chemicals that rush to the site. You can think of your immune system as an ambulance that comes roaring to the rescue after an accident.

But suppose the ambulance driver is so anxious to reach you that he crashes right through the side of your house? That’s inflammation—the negative side effects of the healing process.

The four classic inflammatory responses are redness, heat, pain and swelling, symptoms that are easily visible when the injury can be seen. Think of how a cut on your finger turns red and how warm and tender the skin becomes, or imagine how a bugbite on your ankle might swell. Those reactions occur inside your body, too, when a high-FI food triggers an immune reaction. Your digestive tract becomes inflamed. If you frequently eat foods that inflame your system—either foods to which you’re sensitive or foods that contain inflammatory fats (e.g., dairy, eggs and corn)—then you’re likely to suffer from chronic low-grade inflammation. And you’re running the risk of weight-loss resistance and obesity.

Inflammation puts on the pounds in a number of different ways.

Inflammation puts on the pounds in a number of different ways:

  • Chemical changes.
    Inflammation makes your body resistant to key chemical messengers that help you burn fat, tolerate stress and normalize your appetite and cravings. For example, inflammation
    keeps your body from “hearing” cortisol, the key stress hormone. As a result, your cortisol levels rise, stressing you out, storing fat around your waist and causing you to crave carbs. Cortisol also lowers your serotonin, the feel-good brain chemical that helps you feel calm and optimistic and sleep well. Eventually, your body gets tired of producing all that excess cortisol, and your levels drop, causing you to feel sluggish, unmotivated and fatigued.

Inflammation also creates resistance to leptin, the hormone that regulates feelings of hunger and fullness. Leptin resistance means that leptin can’t get into your cells. This makes you hungrier, so you eat more, well past the point where your brain would normally be signaling “enough.”

Finally, inflammation keeps your body from responding properly to adiponectin, which helps regulate blood sugar and body fat. Add up all these responses, and you get weight gain.

  • Insulin resistance.
    Insulin is a hormone that moves sugar out of your bloodstream and into your cells. When I say, “sugar,” I don’t just mean the sweet white stuff that sits on the table. I mean the starches found in grains, the fructose and glucose found in fruits and vegetables and the lactose found in milk. These sugars enter your blood, where they are meant to provide energy for your body and brain, as long as insulin helps move them into your cells.

Insulin resistance slams the doors to your fat cells shut.

But when you are consuming too much sugar (in the form of sweets, starches or dairy products) or when your system is inflamed, your body secretes too much insulin and keeps the insulin in your bloodstream longer than it’s supposed to. After a while, your cells can’t “hear”
all that excess insulin. Your insulin receptors stop responding to the insulin, and your blood sugar remains high. You may eventually have trouble manufacturing enough insulin, putting you at risk for diabetes. Meanwhile, you can’t use that extra blood sugar for energy, and it ends up getting stored as fat.

In addition, all that excess insulin in your blood tells your body you have enough sugar around for fuel, so it doesn’t need to burn stored fat. Insulin resistance basically slams the doors to your fat cells shut. Insulin resistance also makes it nearly impossible to lose weight. And inflammation virtually guarantees that you will suffer from insulin resistance.

  • Fluid retention.
    Inflammation doesn’t just help you hold onto your body fat, it also causes you to retain fluids so you feel bloated and heavy.
  • Digestive problems.
    When inflammation rages through your intestines, your digestive system can’t operate efficiently. If you have an imbalance of gut bacteria, with more bad bacteria than good, you will actually extract more calories from the food you eat and store them as fat. If your gut wall is damaged and leaky, you will struggle to be able to absorb your nutrients. The result is that even though you are eating, you still feel hungry and unsatisfied because your body can’t get what it needs from your food.
  • Loss of energy.
    Inflammation causes you to feel sluggish and fatigued. If your body is inflamed, you are not going to feel like moving much, so you become even more sedentary. The less active you are, the more resistant to insulin you become—and the vicious cycle continues.

I hope you’re beginning to see why I told Leslie to pull out of her diet any high-FI foods that might be causing an inflammatory response. The fastest way to gain weight that you can’t lose is to allow your body to become inflamed. And the fastest way to drop those extra pounds is to remove the sources of inflammation and let your body heal. That’s what the Virgin Diet is all about.

INFLAMMATION: A SERIOUS WARNING SIGN

If you want to know whether your body is inflamed, ask your physician to test your blood for high-sensitivity C-reactive protein (hs-CRP). Even a slightly elevated hs-CRP level is associated with obesity and weight gain—and even worse, it’s a predictor of diabetes, heart attack and stroke. Luckily, the Virgin Diet can help you bring those levels down quickly.

FAT MAKES MORE FAT

As we just saw, inflammation causes you to gain and retain weight in several different ways—and those extra fat cells don’t just sit there, either. They release more inflammatory chemicals, creating the mother of all vicious cycles. Inflammation can lead to obesity. And fat—especially belly fat—releases inflammatory chemicals called
cytokines,
which are messengers that your body uses to start the inflammatory process. So your fat cells are
producing more inflammatory messengers, and all that inflammation is making you gain more weight, and then your fat is basically making you
more
fat! How unfair is that?

Fat releases inflammatory chemicals called
cytokines
.

So all that extra fat you might be carrying around is not benign, like a backpack. It’s more like carrying a bomb in your backpack. It’s why I want you to lose fat quickly and lower inflammation quickly by pulling the 7 high-FI foods from your diet.

Following the Virgin Diet will also help you overcome insulin resistance. As part of the program, you’ll eat every 4 to 6 hours and stick to moderate portion sizes of clean, lean protein; healthy fats; high-fiber, low-glycemic carbs; and nonstarchy vegetables. (I go into more detail about the program in
Chapter 8
.) This is the fastest way I know to get your blood sugar levels balanced and your insulin working efficiently once more.

HOW YOU CREATE INFLAMMATION

  • Eating foods to which your body is sensitive, allergic or intolerant
  • Eating sugar, artificial sweeteners and processed and high-glycemic carbohydrates
  • Eating pro-inflammatory fats, such as those found in eggs, corn and dairy
  • Eating trans and damaged fats
  • Having abdominal fat
INFLAMMATION AND LEPTIN RESISTANCE

Inflammation doesn’t only create insulin resistance. It also creates leptin resistance, which makes it even harder for you to lose weight.

Leptin is a hormone that responds to how much you’ve eaten and signals the brain that you’ve had enough (
satiety
is the technical term). Leptin also helps burn fat by cueing your metabolism to run faster when you have extra fat to burn and slowing down your metabolism when your body needs to hold onto fat. You can see how our ancestors might have needed this hormone to help adjust their metabolisms depending on whether food was plentiful or scarce.

When leptin is working well, you eat until you don’t need any more food and then you stop. When your system is leptin-resistant, you have a lot of leptin circulating in your blood, but your brain can’t “hear” it. You end up with too much leptin in your blood and not enough in your brain. That’s the situation for the vast majority of overweight people. As a result, they experience increased hunger, food cravings and weight gain. Even though they’re overweight, their bodies believe they’re hungry and go into a state of fat storage.

If you want to lose that extra weight, you have to heal the leptin resistance. Healing inflammation will go a long way toward getting your leptin working properly again. And pulling the high-FI foods is key.

If you want to lose that extra weight, you have to heal the leptin resistance.

Meanwhile, if you keep eating high-FI foods, you continue to feed the problem. You might think you are making healthy choices with your nonfat yogurt, omega-3–rich eggs and low-fat soy milk, but every bite of high-FI food is potentially triggering an immune response that could
flood your body with inflammatory chemicals and start the whole cycle over again. So basically, any time you eat a problem food, you’re setting yourself up for weight gain.

All of the top 7 high-FI foods are potential sources of inflammation, which is why it’s so important to pull them from your diet. Once you do so, your inflammation will disappear, your symptoms will disappear—and those extra pounds will disappear, too.

Any time you eat a problem food, you’re setting yourself up for weight gain.

WHEN GOOD DIGESTION GOES BAD

There is another factor that might be making you fat and old before your time: poor digestion. When digestion works well, it is a beautiful thing, but when it’s out of whack, it can be a huge contributor to weight gain.

Bacteria, also known as flora or gut flora, is crucial to good digestion. Believe it or not, we have more than 500 species of different bacteria in our gastrointestinal tract. In fact, we have more bacteria than we have cells. Most of that bacteria is good for us; it helps break down food, absorb nutrients and keep our immune systems primed. Some of that bacteria is bad—the kind that attacks our cells or produces toxins.

The key thing with gut bacteria is making sure that we have the ideal amount of good bacteria that we need. So, focus on promoting the good bacteria that will help support your gut immune system and keep the bad bacteria at bay.

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