Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (1003 page)

   After allogeneic bone marrow transplantation

Decreased In

   Hereditary deficiencies

   Acquired immunodeficiency

   Non-IgD myeloma

   Infancy, early childhood

   Limitations

   An elevated IgD need to be identified as monoclonal or polyclonal by immunofixation method.

IMMUNOGLOBULIN E (IgE)

   Definition

   IgE mediates allergic and hypersensitivity reactions. There is a significant overlap in total IgE between allergic and nonallergic individuals. Measurement of total IgE is not very useful as a standalone screen for allergy disease.

   
Normal values:
see Table 16.42.

TABLE 16–42. Normal Values for IgE by Age

   Use

   For allergy testing; IgE antibodies and skin tests are essentially interchangeable.

   Indicates various parasitic diseases.