Authors: Mary A. Williamson Mt(ascp) Phd,L. Michael Snyder Md
Blood glucose normally falls to 50% of fasting level within 20–30 minutes and returns to fasting level within 90–120 minutes.
Blood glucose that falls <25% and returns rapidly to fasting level represents an increased tolerance to insulin.
Increased In
Hypothyroidism
Acromegaly
Cushing syndrome (peak cortisol response <18–20 μg/dL and change over baseline <7 μg/dL indicate glucocorticoid deficiency)
DM (some patients; especially older, obese ones)
Decreased In
Increased sensitivity to insulin (excessive fall of blood glucose)
Hypoglycemic nonresponsiveness (lack of response by glycogenolysis)
Pancreatic islet cell tumor
Adrenocortical insufficiency
Adrenocortical insufficiency secondary to hypopituitarism
Hypothyroidism
von Gierke disease (some patients)