Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (1031 page)

   Hemosiderosis of excessive iron intake (e.g., repeated blood transfusions, iron therapy, iron-containing vitamins) (may be >300 μg/dL)

   Decreased formation of RBCs (e.g., thalassemia, pyridoxine deficiency anemia, PA in relapse)

   Increased destruction of RBCs (e.g., hemolytic anemias)

   Acute liver damage (degree of increase parallels the amount of hepatic necrosis) (may be >1,000 μg/dL); some cases of chronic liver disease

   Progesterone birth control pills (may be >200 μg/dL) and pregnancy

   Premenstrual elevation by 10–30%

   Acute iron toxicity; serum iron-to-TIBC ratio is not useful for this diagnosis

   Repeated transfusions

   Lead poisoning

   Acute hepatitis

   Vitamin B
₆
deficiency

Decreased In

   Iron deficiency anemia

   Normochromic (normocytic or microcytic) anemias of infection and chronic diseases (e.g., neoplasms, active collagen diseases)