Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (1035 page)

   
% Saturation
=
Serum iron/TIBC
×
100

   
Normal range:
20–50%.

   Use

   Differential diagnosis of anemias

   Screening for hereditary hemochromatosis

   Interpretation

Increased In

   Hemochromatosis

   Hemosiderosis

   Thalassemia

   Birth control pills (≤75%)

   Ingestion of iron (≤100%)

   Iron dextran administration causes increase for several weeks (may be >100%)

   Vitamin B
₆
deficiency

   Aplastic anemias