Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (1070 page)

   Hypothyroidism

   Hemolysis with high reticulocyte count

   Infants and newborns

Decreased In

   Iron deficiency anemias

   Thalassemias

   Hereditary sideroblastic anemia

   Lead poisoning

   Anemia of chronic disease and other hemoglobinopathies (may be decreased or normal)

   Limitations

   MCV may be artificially increased with marked leukocytosis, numerous large platelets, cold agglutinins, methanol poisoning, marked hyperglycemia, and marked reticulocytosis.

   MCV may be falsely decreased with in vitro hemolysis or fragmentation of RBCs.

MEAN PLATELET VOLUME (MPV)
^†

   Definition

   MPV reflects the frequency distribution of platelet volumes.

   
Normal range:
7.8–11.0 fL.