Authors: Mary A. Williamson Mt(ascp) Phd,L. Michael Snyder Md
Iron deficiency anemia
Estrogen, pregnancy, or anabolic steroids
Increase comigrates with transferrin, Hb (in excess to that bound in Hb-Hp complexes)
Acute inflammation (later phase)
Monoclonal immunoglobulins (IgA is frequent)
Double bands
Transferrin phenotypes (different degrees of sialation)
Alcoholics
Gammaglobulin
Polyclonal gammopathy: chronic, subacute infections (AIDS, hepatic infections, chronic liver associated with beta–gamma bridging, autoimmune disorders)
Narrow band: monoclonal component, monoclonal gammopathy of undetermined significance, fibrinogen, CRP
Two narrow bands:
Biclonal or double gammopathies