Authors: Mary A. Williamson Mt(ascp) Phd,L. Michael Snyder Md
Use
Monitoring exposure to organophosphorus insecticides
Monitoring patients with liver disease, particularly those undergoing liver transplantation
Identifying patients who are homozygous for the atypical gene and have low levels of PChE that are not inhibited by dibucaine
Identifying patients, who are heterozygous for the atypical gene and have lower than normal levels of PChE and varying levels of inhibition with dibucaine
Interpretation
Increased In
Type IV hyperlipoproteinemia
DM
Hyperthyroidism
Insecticide exposure (organophosphates)
Nephritic syndrome
Psychosis
Breast cancer
Decreased In
Genetic PChE variants