When Science Goes Wrong (44 page)

R Buchert, R Thomasius, et al. (2006). ‘Reversibility of ecstasy-induced reduction in serotonin transporter availability in polydrug ecstasy users.’
European Journal of Nuclear Medicine and Molecular Imaging
33:188-99.

News Accounts:

DG McNeil, Jr (2003). ‘Research on Ecstasy Is Clouded by Errors.’
New York Times
, December 2.

R Walgate (2002). ‘Independent inquiry demanded into Ecstasy affair.’
The Scientist
, September 18.

R. Highfield (2002). ‘Ecstasy Use “May Lead to Parkinson’s-type Illness.”’
The Daily Telegraph
, September 27.

Other:

Charles Grob: Testimony before the US Sentencing Commission on MDMA. Available at: www.maps.org/news/grobtestimony.html.

Congressional Record, June 18, 2002: Reducing Americans’ Vulnerability to Ecstasy Act of 2002. Available at: frwebgate.access

.gpo.gov/cgibin/useftp.cgi?IPaddress=162.140.64.31&filename=s2633is.txt&directory=/disk2/wais/data/107_cong_bills.

Drug Enforcement Agency (2002). Statement of Asa Hutchinson before the House Judiciary Subcommittee on Crime, Terrorism and Homeland Security. Available at: www.usdoj.gov/

dea/pubs/cngrtest/ct101002.html.

National Institute on Drug Abuse: Director’s Report to the National Advisory Council on Drug Abuse – February 2003. Available at: www.drugabuse.gov/DirReports/DirRep203/Director

Report1.html.

Emergency Department Trends from the Drug Abuse Warning Network, 1994-2001. Available at: www.oas.samhsa.gov/DAWN/

Final2k1Edtrends/text/Edtrend2001v6.pdf.

CNN Student News (2000). Famous fried eggs: Students debate effectiveness, accuracy of well-known anti-drug commercial. Available at: www.cnnstudentnews.cnn.com/fyi/interactive/news

/brain/brain.on.drugs.html.

Multidisciplinary Association for Psychedelic Studies (2004). NIDA and NCRR funding for Ricaurte and McCann 1989-2003. Available at: www.maps.org/mdma/ricaurtefunding.pdf.

Multidisciplinary Association for Psychedelic Studies (undated). NIDA Grant Progress Report, George A Ricaurte, Principal Investigator, July 17, 2003, (obtained by an FOIA request). Available at: adgjm.net/ura/ua.cgi?ul=http%3A%2F%2Fwww.maps

.org%2Fmdma%2Fretraction%2Ffoia012804%2Fprogress1.html&ua=.

Interviews:

Jack Green, PhD, March 1, 2006.

Books:

Charles F Outland (1963, revised 2002).
Man-Made Disaster: The Story of St Francis Dam
. Historical Society of Southern California and Vroman’s Bookstore.

Doyce B Nunis., ed. (2002).
The St Francis Dam Disaster Revisited
. Historical Society of Southern California and Vroman’s Bookstore.

Scientific Publications:

JD Rogers (2002). ‘A man, a dam, and a disaster: Mulholland and the St Francis Dam.’ In Nunis (see page 278), pp 1-109.

Other:

AJ Wiley, GD Louderback, FL Ransome, et al. (1928). Report of the Commission Appointed by Governor CC Young to Investigate the Causes Leading to the Failure of the St Francis Dam near Saugus, California. State of California.

JD Rogers. Failure of the St Francis Dam. Available at: http://

web.mst.edu/~rogersda/st_francis_dam/index.htm.

Jack Green. St Francis Dam. Available at: http://seis.natsci.csulb

.edu/VIRTUAL_FIELD/Francesquito_Dam/franmain.htm.

Goutal, N. The Malpasset Dam failure: An overview and test case definition. Available at: www.hrwallingford.co.uk/projects/

CADAM/CADAM/zaragoza/z2.pdf.

Interviews:

Arthur Caplan, PhD, November 24, 2006.

Paul Gelsinger, November 27, 2006 (and subsequent email correspondence).

Robert Erickson, MD, December 6, 2006.

Inder Verma, PhD, December 4, 2006.

Scientific Publications:

X Ye, MB Robinson, ML Batshaw, et al. (1996). Prolonged metabolic correction in adult ornithine transcarbamylase-deficient mice with adenoviral vectors.
Journal of Biological Chemistry
271:3639-46.

National Institutes of Health Recombinant DNA Advisory Committee (2002). Assessment of adenoviral vector safety and toxicity.
Human Gene Therapy
13:3-13.

DA Sisti and AL Caplan (2003). Back to basics: Gene therapy research ethics and oversight in the post-Gelsinger era. In
Ethik und Gentherapie: Zum praktischen Diskurs um die molekulare Medizin
(C Rehmann-Sutter and H Müller eds.), Francke Verlag.

G Suntharalingam, MR Perry, S Ward, et al. (2006). Cytokine storm in a phase-1 trial of the anti-CD28 monoclonal antibody TGN1412.
New England
Journal of Medicine
355:1018-1028.

News Accounts:

SG Stolberg (1999). ‘The Biotech Death of Jesse Gelsinger.’
New York Times
(November 28).

SG Stolberg (1999). ‘FDA Officials Fault Penn Team in Gene Therapy Death.”
New York Times
(December 9).

D Nelson and R Weiss (1999). ‘Hasty Decisions in the Race to a Cure? Gene Therapy Study Proceeded Despite Safety, Ethics Concerns.”
Washington
Post
(November 21).

E Marshall
(2000). ‘Gene Therapy on Trial.’ Science 288:951-957.

D Sanderson (2006). ‘I Was Treated No Better Than An Animal, Says Drug victim.’
The Times
(March 31).

D Leppard (2006). ‘Elephant Man Drug Victims Told To Expect Early Death.’
The Sunday Times
(July 30).

E Rosenthal
(2006). ‘Ill-fated UK Drug Trial Bares Testing Loop Holes.’
International Herald Tribune
(July 30).

Other:

FDA: Letter to James Wilson dated March 3, 2000: http://www.fda.gov/foi/warning_letters/archive/m3435n.pdf.

FDA: Letter to James Wilson dated February 8, 2002: www.fda.gov/foi/nooh/Wilson.htm.

FDA: Letter to Mark Batshaw dated November 30, 2000: www.fda.gov/foi/nidpoe/n14l.pdf.

Institute for Human Gene Therapy (2000): Institute for Human Gene Therapy Responds to FDA (press release, February 14). www.upenn.edu/almanac/between/FDAresponse.html.

United States Attorney’s Office, Eastern District of Pennsylvania (2006). US settles case of gene therapy study that ended with teen’s death (press release, February 9). Available at: http://www.upenn.

edu/almanac/volumes/v51/n21/gts.html.

P Gelsinger (2001). Jesse’s intent. www.circare.org/jintent.pdf.

Independent panel reviewing the University of Pennsylvania’s Institute for Human Gene Therapy (2000). Report. Available at: www.upenn.edu/almanac/v46/n34/IHGT-review.html.

JM Wilson (1999). Presidential address, American Society of Gene Therapy. web.archive.org/web/20001210180800/www.med.

upenn.edu/~ihgt/info/asgt99.html.

Interviews:

Stephen Hanauer, 2005 (date unknown).

Books:

William McKeown (2003). Idaho Falls: The Untold Story of America’s First Nuclear Accident. ECW Press.

Susan M Stacy (2000). Proving the Principle: A History of the Idaho National Engineering and Environmental Laboratory, 1949-1999. US Government Printing Office.

Other

Arlington National Cemetery Web site: Richard Leroy McKinley. www.arlingtoncemetery.net/rlmckinl.htm.

US Atomic Energy Commission, Idaho Operations Office.
The SL-1
Accident. Distributed by Radiationworks.com (documentary film).

Interviews:

Ken Alibek, April 13, 2006.

Jeanne Guillemin, April 2006 (email correspondence).

Peter Gumbel, April/May 2006 (email correspondence).

Matthew Meselson, April 17, 2006.

Books:

Ken Alibek (1999). Biohazard: The Chilling True Story of the Largest Covert Biological Weapons Program in the World – Told from the Inside by the Man Who Ran It. Random House.

Jeanne Guillemin (1999). A
nthrax: The Investigation of a Deadly Outbreak
. University of California Press.

Tom Mangold and Jeff Goldberg (1999).
Plague Wars: The Terrifying Reality of Biological Warfare
. St. Martin’s Press.

Judith Miller, Stephen Engelberg and William Broad (2001).
Germs: Biological Weapons and America’s Secret War
. Simon & Schuster.

Scientific Publications:

M Meselson, J Guillemin, J Martin Hugh-Jones, et al. (1994). The Sverdlovsk anthrax outbreak of 1979.
Science
, 266:1202-1208.

JB Tucker, The ‘Yellow Rain’ controversy. Lessons for arms control compliance.
The Nonproliferation Review
, Spring 2001, pp 25-42.

J Guillemin (2002). The 1979 anthrax epidemic in the USSR: Applied science and political controversy.
Proceedings of the American Philosophical Society
, 146:18-36. Available at: www.aps-pub.com/proceedings/1461/102.pdf.

DA Wilkening (2006). Sverdlovsk revisited: Modeling human inhalation anthrax.
Proceedings of the National Academy of Sciences
, 103:7589-7594.

Other:

Robert A Wampler and Thomas S Blanton (eds.). The National Security Archive – Volume V: Anthrax at Sverdlovsk, 1979. Available at: www.gwu.edu/~nsarchiv/NSAEBB/NSAEBB61/.

Interviews:

William Thompson, JD, PhD, July 7, 2006.

Scientific Publications:

WC Thompson, F Taroni; and CGG Aitken (2003). How the probability of a false positive affects the value of DNA evidence.
Journal of Forensic Science
. 48:1-8.

News Accounts:

MA Fergus, (2004). ‘Josiah Sutton: One Year Later.’
Houston
Chronicle
, March 6.

R Khanna, (2006). ‘In a Lot of Ways, I Still Am Suffering.’
Houston
Chronicle
, June 23.

M Possley (2006). ‘Inmate Wrongly Executed.’
Chicago
Tribune
, May 3.

Associated Press (2006). ‘Experts Question Arson Convictions.’ May 7. Available at: spd.iowa.gov/filemgmt_data/files/arson.pdf.

R Khanna and S McVicker (2004). ‘Fired DNA Analyst to Return to Work at Crime Lab.’
Houston
Chronicle
, January 27.