Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (329 page)

   Infections in conjunction with neutrophilia

   Inflammation: acute

BASOPHILIA

   Definition

Basophilia is defined as >300/μL or >2% of leukocytes. (The basophil is the rarest of leukocytes.)

   Associated Conditions

   Basophilia frequently accompanies myeloproliferative neoplasms, and its progression may herald a blast crisis in chronic myelogenous leukemia. The existence of basophilic leukemia is controversial. One case was recently described by our group.

   Other causes of basophilia are

   Hypersensitivity states (drugs, foods, foreign protein injection)

   Myxedema

   Anemias, chronic hemolytic, iron deficiency (in some patients)

   Ulcerative colitis

   Postsplenectomy

   Hodgkin lymphoma

   Chronic sinusitis