Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (1134 page)

   Diagnosis of familial hyperkalemic periodic paralysis and hypokalemic paralysis

   Interpretation

Increased In

   Potassium retention

   GFR <3–5 mL/minute

   Oliguria caused by any condition (e.g., renal failure)

   Chronic nonoliguric renal failure associated with dehydration, obstruction, trauma, or excess potassium

   Drugs

   Renal toxicity (e.g., amphotericin B, methicillin, tetracycline)

   GFR >20 mL/minute

   Decreased (aldosterone) mineralocorticoid activity

   Addison disease

   Hypofunction of the renin–angiotensin–aldosterone system

   Hyporeninemic hypoaldosteronism with renal insufficiency (GFR, 25–75 mL/minute)