Authors: Mary A. Williamson Mt(ascp) Phd,L. Michael Snyder Md
Glutethimide:
gas chromatography, GC/MS, liquid chromatography, LC/ MS; measure parent and active metabolite hydroxyglutethimide
Methaqualone:
immunoassay screening test available for this agent
Target analyte—methaqualone
Cutoff concentration (urine)]—300 ng/mL
Confirmation by gas chromatography, GC/MS, liquid chromatography, LC/MS: limit of quantitation: 50–200 ng/mL
Meprobamate
Older CNS depressant
Metabolite of muscle relaxant carisoprodol
No immunoassay-based screening tests available
Readily extracted in acidic neutral liquid–liquid or solid-phase extraction scheme: GC, GC/MS, liquid chromatography, LC/MS; limit of quantitation: 500–1,000 ng/mL
Buspirone
Newer antianxiety drug
No immunoassay-based screening tests available