Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (1202 page)

BOOK: Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis
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Glutethimide:
gas chromatography, GC/MS, liquid chromatography, LC/ MS; measure parent and active metabolite hydroxyglutethimide
   
Methaqualone:
immunoassay screening test available for this agent
   Target analyte—methaqualone
   Cutoff concentration (urine)]—300 ng/mL
   Confirmation by gas chromatography, GC/MS, liquid chromatography, LC/MS: limit of quantitation: 50–200 ng/mL
   
Meprobamate
   Older CNS depressant
   Metabolite of muscle relaxant carisoprodol
   No immunoassay-based screening tests available
   Readily extracted in acidic neutral liquid–liquid or solid-phase extraction scheme: GC, GC/MS, liquid chromatography, LC/MS; limit of quantitation: 500–1,000 ng/mL
   
Buspirone
   Newer antianxiety drug
   No immunoassay-based screening tests available

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