Authors: Mary A. Williamson Mt(ascp) Phd,L. Michael Snyder Md
Maple syrup urine disease
Down syndrome
Polycystic kidneys
Calcinosis universalis and circumscripta
Hypoparathyroidism
Primary hyperparathyroidism
Hypothyroidism
Sarcoidosis
Chronic berylliosis
Patients with arteriosclerosis and hypertension (serum uric acid is increased in 80% of patients with elevated serum triglycerides)
Certain population groups (e.g., Blackfoot and Pima Indians, Filipinos, New Zealand Maoris)
Most common causes in hospitalized men are azotemia, metabolic acidosis, diuretics, gout, myelolymphoproliferative disorders, other drugs, unknown causes.
It is difficult to justify therapy in asymptomatic persons with hyperuricemia to prevent gouty arthritis, uric acid stones, urate nephropathy, or risk of cardiovascular disease.