Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (1271 page)

Decreased In

   Drugs

   ACTH

   Uricosuric drugs (e.g., high doses of salicylates, probenecid, cortisone, allopurinol, coumarin)

   Various other drugs (radiographic contrast agents, glyceryl guaiacolate, estrogens, phenothiazines, indomethacin)

   Wilson disease

   Fanconi syndrome

   Acromegaly (some patients)

   Celiac disease (slightly)

   PA in relapse (some patients)

   Xanthinuria

   Neoplasms (occasional cases) (e.g., carcinomas, Hodgkin disease)

   Healthy adults with isolated defect in tubular transport of uric acid (Dalmatian dog mutation)

   Decreased in approximately 5% of hospitalized patients; most common causes are postoperative state (GI surgery, coronary artery bypass), DM, various drugs, and SIADH in association with hyponatremia

Unchanged In