Secondary Schizophrenia (28 page)

and falls of disconnection

development and neuropathology

clozapine-responsive patients.

syndromes. Brain, 2005.

in schizophrenia. In Development

Pharmacopsychiatry, 2007.

128
:2224–39.

of the Cerebral Cortex, vol
193
,
40
:157–62.

Block G. (Ed.). New York: J. Wiley,

36. Andreasen N. C., Paradiso S.,

27. Hoshi Y., Shinba T., Sato C.,
et al.

pp. 277–95.

O’Leary D. S. “Cognitive

Resting hypofrontality in

dysmetria” as an integrative

47. Jones, E. Cortical development

schizophrenia: a study using

theory of schizophrenia: a

and thalamic pathology in

near-infrared time-resolved

dysfunction in cortical–

schizophrenia. Schizophr Bull,

spectroscopy. Schizophr Res, 2006.

subcortical–cerebellar circuitry?

1997.
23
:483–501.

84
:411–20.

Schizophr Bull, 1998.
24
:203–18.

48. Davis K. L., Stewart D. G.,

28. Shinba T., Nagano M., Kariya N.,

37. Friston K. J., Frith C. D.

Friedman J. I.,
et al.
White matter

et al.
Near-infrared spectroscopy

Schizophrenia: a disconnection

changes in schizophrenia:

analysis of frontal lobe

syndrome? Clin Neurosci, 1995.

evidence for myelin-related

dysfunction in schizophrenia. Biol

3
:89–97.

dysfunction. Arch Gen Psychiatry,

Psychiatry, 2004.
55
:154–64.

2003.
60
:443–56.

38. Goldberg E., Bilder R. M., Hughes

29. Watanabe A., Kato T.

49. Kubicki M., McCarley R. W.,

J. E.,
et al.
A reticulo-frontal

Cerebrovascular response to

Shenton M. E. Evidence for white

disconnection syndrome. Cortex,

cognitive tasks in patients with

matter abnormalities in

1989.
25
:687–95.

schizophrenia measured by

schizophrenia. Curr Opin

near-infrared spectroscopy.

39. Swerdlow N., Koob G. Dopamine,

Psychiatry, 2005.
18
:121–34.

Schizophr Bull, 2004.
30
:435–44.

schizophrenia, mania, and

50. Buchsbaum M. S., Buchsbaum B.

depression: towards a unified

30. Fallgatter A. J., Strik W. K.

R., Hazlett E. A.,
et al.
Relative

hypothesis of cortico-striato-

Reduced frontal functional

glucose metabolic rate higher in

palido-thalamic function. Behav

asymmetry in schizophrenia

white matter in patients with

Brain Sci, 1987.
10
:197–245.

during a cued continuous

schizophrenia. Am J Psychiatry,

performance test assessed with

40. Beaumont J. G., Dimond S. J.

2007b.
164
:1072–81.

near-infrared spectroscopy.

Brain disconnection and

51. Clark C. M., Kessler R.,

Schizophr Bull, 2000.
26
:
schizophrenia. Br J Psychiatry,

Buchsbaum M. S.,
et al.

913–19.

1973.
123
:661–2.

Correlational methods for

31. Kubota Y., Toichi M., Shimuzu

41. Friston K. J. The disconnection

determining regional coupling of

M.,
et al.
Prefrontal activation

hypothesis. Schizophr Res, 1998.

cerebral glucose metabolism: a

during verbal fluency tests in

30
:115–25.

pilot study. Biol Psychiatry, 1984.

schizophrenia–a near-infrared

42. Friston K. J. Schizophrenia and

19
:663–78.

spectroscopy (NIRS) study.

the disconnection hypothesis.

52. Horwitz B., Duara R., Rapoport S.

Schizophr Res, 2005.
77
:
Acta Psychiatr Scand Suppl, 1999.

I. Intercorrelations of glucose

65–73.

395
:68–79.

metabolic rates between brain

32. Okada F., Tokumitsu Y., Hoshi Y.,

43. Stephan K. E., Baldeweg T.,

regions: application to healthy

et al.
Impaired interhemispheric

Friston K. J. Synaptic plasticity

males in a state of reduced

integration in brain oxygenation

and disconnection in

sensory input. J Cereb Blood Flow

and hemodynamics in

schizophrenia. Biol Psychiatry,

Metab, 1984.
4
:484–99.

schizophrenia. Eur Arch

2006.
59
:929–39.

53. Horwitz B. Simulating functional

Psychiatry Clin Neurosci, 1994.

44. Bullmore E. T., Frangou S.,

interactions in the brain: a model

244
:17–25.

Murray R. M. The dysplastic net

for examining correlations

33. Suto T., Fukuda M., Ito M.,
et al.

hypothesis: an integration of

between regional cerebral

Multichannel near-infrared

developmental and

metabolic rates. Int J Biomed

spectroscopy in depression and

dysconnectivity theories of

Comput, 1990.
26
:149–70.

schizophrenia: cognitive brain

schizophrenia. Schizophr Res,

54. Horwitz B. Functional

activation study. Biol Psychiatry,

1997.
28
:143–56.

interactions in the brain: use of

2004.
55
:501–11.

45. Bullmore E. T., Woodruff P. W.,

correlations between regional

34. ffytche D. H., Catani M. Beyond

Wright I. C.,
et al.
Does dysplasia

metabolic rates. J Cereb Blood

localization: from hodology to

cause anatomical dysconnectivity

Flow Metab, 1991.
11
:A114–A120.

function. Phil Trans R Soc B, 2005.

in schizophrenia? Schizophr Res,

55. Katz M., Buchsbaum M. S., Siegel

69

360
:767–79.

1998.
30
:127–35.

B. V. Jr.,
et al.
Correlational

The Neurology of Schizophrenia – Section 2

patterns of cerebral glucose

effective connectivity in drug free

Cortical-striatal-thalamic circuits

metabolism in never-medicated

schizophrenic patients.

and brain glucose metabolic

schizophrenics.

Neuroreport, 2003b.
14
:2233–7.

activity in 70 unmedicated male

Neuropsychobiology, 2006.

64. Brown G. G., Eyler L. T.

schizophrenic patients. Am J

33
:1–11.

Methodological and conceptual

Psychiatry, 1993.
150
:1325–36.

56. Kessler R. M., Clark C. M.,

issues in functional magnetic

73. Volkow N. D., Wolf A. P., Brodie

Buchsbaum M. S.,
et al.
(1983).

resonance imaging: applications

J. D.,
et al.
Brain interactions in

Regional correlations in patterns

to schizophrenia research. Annu

chronic schizophrenics under

of glucose use in patients with

Rev Clin Psychol, 2006.
2
:
resting and activation condition.

schizophrenia and normal

51–81.

Schizophr Res, 1988.
1
:47–53.

subjects during mild pain

65. Snellenberg J. X. van, Torres I. J.,

74. Fujimoto T., Takeuch K.,

stimulation. In Positron Emission

Thornton A.E. Functional

Matsumoto T.,
et al.
Abnormal

Tomography of the Brain, W. D.

neuroimaging of working

glucose metabolism in the

Heiss and M. E. Phelps (Eds.).

memory in schizophrenia: task

anterior cingulate cortex in

Berlin: Springer Verlag,

performance as a moderating

patients with schizophrenia.

pp. 196–200.

variable. Neuropsychology, 2006.

Psychiatry Res, 2007.
154
:49–58.

57. Friston K. J. Functional and

20
:497–510.

75. Haznedar M. M., Buchsbaum M.

effective connectivity: a synthesis.

66. Mitelman S. A. Byne W.,

S., Hazlett E. A.,
et al.
Cingulate
Hum Brain Mapp, 1994.
2
:
Kemether E. M.,
et al.
Metabolic

gyrus volume and metabolism in

56–78.

thalamocortical correlations

the schizophrenia spectrum.

58. Lagreze H. L. Hartmann A.,

during a verbal learning task and

Schizophr Res, 2004.
71
:249–62.

Anzinger G.,
et al.
Functional

their comparison with

76. Yücel M., Brewer W. J., Harrison

cortical interaction patterns in

correlations among regional

B. J.,
et al.
Anterior cingulate

visual perception and visuospatial

volumes. Brain Res, 2006.

activation in antipsychotic-na¨ıve

problem solving. J Neurol Sci,

1114
:125–37.

first-episode schizophrenia. Acta

1993.
114
:25–35.

67. Weinstein S., Woodward T. S.,

Psychiatr Scand, 2007.
115
:
59. McIntosh A. R. Gonzalez-Lima F.

Ngan E. T. Brain activation

155–8.

Network interactions among

mediates the association between

77. Kim J. J., Seok J. H., Park H. J., et
limbic cortices, basal forebrain,

structural abnormality and

al. Functional disconnection of

and cerebellum differentiate a

symptom severity in

the semantic networks in

tone conditioned as a Pavlovian

schizophrenia. Neuroimage, 2007.

schizophrenia. Neuroreport, 2005.

excitor or inhibitor: fluoro-

36
:188–93.

16
:355–9.

deoxyglucose mapping and

68. Mitelman S. A., Shihabuddin L.,

78. Shihabuddin L., Buchsbaum M.

covariance structural modeling.

Brickman A. M.,
et al.
Cortical

S., Hazlett E. A.,
et al.
Dorsal

J Neurophysiol, 1994.
72
:1717–33.

intercorrelations of temporal area

striatal size, shape, and metabolic

60. McIntosh A. R., Grady C. L.,

volumes in schizophrenia.

rate in never-medicated and

Ungerleider L. G.,
et al.
Network
Schizophr Res, 2005.
76
:207–29.

previously medicated

analysis of cortical visual

69. Mitelman S. A., Buchsbaum M. S.,

schizophrenics performing a

pathways mapped with PET.

Brickman A. M.,
et al.
Cortical

verbal learning task. Arch Gen

J Neurosci, 1994.
14
:655–66.

intercorrelations of frontal area

Psychiatry, 1998.
55
:235–43.

61. Rogers B.P., Morgan V.L., Newton

volumes in schizophrenia.

79. Crespo-Facorro B., Paradiso S.,

A.T.,
et al.
Assessing functional
Neuroimage, 2005.
27
:753–70.

Andreasen N. C.,
et al.
Recalling
connectivity in the human brain

70. Buchsbaum M. S. Positron

word lists reveals “cognitive

by fMRI. Magn Reson Imaging,

emission tomography studies of

dysmetria” in schizophrenia: a

2007.
25
:1347–57.

abnormal glucose metabolism in

positron emission tomography

62. Schlosser R., Gesierich G. T.,

schizophrenic illness. Clin

study. Am J Psychiatry, 1999.

Kaufmann B.,
et al.
Altered

Neurosci, 1995.
3
:122–30.