Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (319 page)

   Tissue or tumor necrosis

   Acute myocardial infarction

   Tumor necrosis

   Burns

   Gangrene

   Bacterial necrosis

   Physiologic conditions

   Strenuous exercise

   Emotional stress

   Labor

   Smoking

   Leukoerythroblastic reaction (myelophthisis): neutrophilia associated with immature granulocytes, nucleated red cells, and teardrop red cells; it is associated with tumor invasion of the bone marrow, TB, and other granulomatous diseases.

NEUTROPENIA

Definition

Less than 43% of leukocytes, or an absolute neutrophil and band count <1,600/ μL (or <1,000/μL in people of African ancestry). Absence of granulocytes: agranulocytosis. A greatly reduced number of neutrophils: granulocytopenia. Absolute neutrophil counts below 500/μL increase susceptibility of bacterial or fungal infections.