Authors: Mary A. Williamson Mt(ascp) Phd,L. Michael Snyder Md
Villous adenoma of colon
Aciduria secondary to potassium depletion
Excess of base caused by administration of
Absorbable antacids (e.g., sodium bicarbonate; milk-alkali syndrome)
Salts of weak acids (e.g., sodium lactate, sodium or potassium citrate)
Some vegetarian diets
Citrate due to massive blood transfusions
Potassium depletion (causing sodium and H
+
to enter the cells):
GI loss (e.g., chronic diarrhea)
Lack of potassium intake (e.g., anorexia nervosa, IV fluids without potassium supplements for treatment of vomiting or postoperatively)
Diuresis (e.g., mercurials, thiazides, osmotic diuresis)
Extracellular volume depletion and chloride depletion
Dehydration, reducing intracellular volume, thereby stimulating aldosterone, causing excretion of potassium and H
+
All forms of mineralocorticoid excess (e.g., primary aldosteronism, Cushing syndrome, administration of steroids, large amounts of licorice) causing excretion of potassium and H
+