Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (824 page)

   Interpretation

Increased In

   Renal patients receiving erythropoietin agents

   ESRD patients undergoing hemodialysis

   Very heavy drinkers of beer with added cobalt

   Individuals with deteriorating metal implants

Decreased In

   NA.

   Limitations

   Diet, medications, supplements (nutritional and mineral), B
₁₂
, or B-complex vitamins may interfere test results. Recommend avoid 3 days prior to testing.

   False-positive test results may occur from using noncertified trace element collection tubes.

   High concentrations of gadolinium and iodine are known to interfere (should wait 96 hours to clear).

   Analysis of cobalt concentration is of little use in the determination of vitamin B
₁₂
deficiency.

   To assess occupational exposure, sample should be collected at the end of the shift on the last day of workweek.

COCAINE
*

   Definition