The Noonday Demon (114 page)

hypericum,
146

hypnosis,
137
,
144

hypnotic drugs,
222

hypothalamic functions,
48
,
55

cortical function and,
448

light stimulation of,
140

hypothyroidism,
289

IAPSRS (International Association of Psychosocial Rehabilitation Services),
368

iatromechanical model,
307
,
481

icebergs,
210
–11

Illiminaq, Greenland,
210
–15

illiteracy,
351

imaging technology, brain metabolism represented in,
254
,
362
,
417

imipramine,
153
–54,
331

immune response:

cortisol employed in,
158

depression as cause of decrease in,
57

of indigent depressed,
345

interleukin-6 in,
146

right-brain activation as predictor of,
418

impotence,
115
,
116

impulsiveness,
253
,
255
,
256

India, train suicides in,
255

individualism,
132

industrial revolution,
320

infancy:

asymmetry of brain activation in,
418

cause/effect linkage developed in,
350

depression in,
181
,
459

see also
childhood depression; children

Inquisition,
293
,
308

insomnia:

drug treatment for,
119

of elderly depressed,
190

suicidality linked to,
146

instinct,
414
–15

institutionalization,
see
hospitals, hospitalization

insurance coverage,
see
health insurance

interleukin-6,
146

International Association of Psychosocial Rehabilitation Services (IAPSRS),
368

interpersonal therapy (IPT),
107
,
109
–10

intimacy, value of,
436

Inuit (Eskimo) peoples, depression in,
208
–15

invention, nature vs.,
430
–31

involuntary-commitment laws,
378

iprindole,
333

iproniazid,
331

irrational fears,
305
–6

irritable bowel syndrome,
65

Islam, holy wars of,
247

isolation,
103
,
214
,
220

isoniazid,
331

Italian Renaissance, melancholia in,
295
–96,
299

Jack, Dana Crowley,
176
–77,
178

Jackson, Stanley,
445
,
478

Jacob’s Room
(Woolf),
16
–17

James, William,
321
,
322
,
328
,
485

James I, King of England,
297

Jamison, Kay Redfield,
445

on adolescent depression,
187

on complexity of brain chemistry,
254

on depression as killer,
57

on emotional range,
412

on family responses to depressed relative,
63

on genetic predisposition to depression,
56

struggle against depression described by,
61
–62

on suicide and suicidality,
254
,
259
–60,
263
,
264
,
265
,
447

Janesson, Ruth Ann,
343
–45,
360

Jefferson, Thomas,
329

Jewish men, depression rates of,
180

Jews, Berlin, suicide rates of,
204
,
465

Joelson, Amalia,
212
,
213
–14

Johansen, Karen,
212
–14

Johns Hopkins University Hospital, psychiatric training at,
328

Johnson, Samuel,
310
,
311

Jones, Nancy Aaron,
459

Joshi, Paramjit T.,
184
,
186
,
460

joy,
443
,
499

depression survivors’ appreciation of,
78
,
434
,
439

see also
happiness

juvenile delinquency,
337

Kaczynski, Theodore (Unabomber),
125
,
454

Kahn, Eve,
82
–83

Kahn, Jack,
404

Kant, Immanuel,
312
,
314
,
315

Kaptur, Marcy,
372
,
373
–74,
378
,
379
,
381

Katz, Ira,
461
–62

kayak anxiety,
213
,
465

kayaking,
143
,
213

Keats, John,
314

Keller, Martin,
104

Kendler, Ken,
450

Kendra’s Law,
380

Kenyon, Jane,
66
,
79

ketamine (Special K),
232

ketoconazole,
58

Kevorkian, Jack,
268

Kharms, Daniil,
77

Khmer Rouge,
32
–35,
351
,
448

kidney stones,
46
–47

Kierkegaard, Søren,
316
,
484

kinesiology,
142

Kleber, Herbert,
219
,
221
,
223
,
224
–25,
230
,
468

Klein, Donald,
103

Klein, Melanie,
326

Klerman, Gerald,
109

Kline, Nathan,
331

Klitzman, Robert,
104
,
436

Klonopin,
83
,
119
,
121
,
234

Kraemer, Gary,
474
,
475

Kraepelin, Emil,
189
,
285
,
323
,
326
–27,
328
,
331
,
450
,
486

Krafft-Ebing, Richard von,
485
–86

Kramer, Peter,
236
,
399

Kristeva, Julia,
52
,
263
,
435
,
440
,
445

Kuhn, Reinhard,
478

Kuhn, Roland,
331

Kye, Christopher,
460

Kyner, Marian,
344
,
349
,
350
–51,
355
,
358
,
359

Lacan, Jacques,
326

La Mettrie, Julien Offray de,
307
–8,
481

Lange, Amelia,
212
,
214

language, asymmetrical brain function and,
416
–17,
418
–19

L-arginine,
116

Last Kings of Thule, The
(Malaurie),
465

Latin culture,
194
–95,
343

Lawlor, B. A.,
462

leadership, political,
367

learned helplessness,
348

Lebou people,
ndeup
ceremonies of,
165

Lemnius, Levinus,
299

Leopardi, Giacomo,
315

lesbians,
202
,
464

Lescol,
422

Levi, Primo,
281
–82

Lévi-Strauss, Claude,
93

Lewin Group,
492

Lewis, Carlita,
349
–50,
360

Lewis, C. S.,
470

Lier, Reinhard,
158
–59,
456

life events, depression triggered by,
62
,
63
,
450

light therapies,
140

limbic system,
49
,
414

Lincoln, Abraham,
329
,
367

listening, parental,
183
,
352

Listening to Prozac
(Kramer),
236
,
366
,
399

lithium,
76
,
83
,
118
,
121
,
383

adverse reaction to,
97

discontinuation of,
126
,
252

suicidality limited by,
252

weight gain with,
161

lobbying groups,
362
–63,
372

lobotomies,
163

locus coeruleus,
65

loneliness,
136
,
214
,
436
–37

long-term demoralization,
351

López, Juan,
59
,
60
,
194
,
343
,
449

Lotbinière, Betsy de,
132
–33

love:

biochemical aspect of,
23
–24

depression as flaw in,
15

evolutionary function of,
412
–14

grief as evidence of,
412
,
435

support found in,
66
,
432
,
436
–37

Luhrmann, T. M.,
101
–2,
104

Lunatics Acts (1845; 1862),
318

Lustral/Zoloft (sertraline),
334

Luvox/Faverin (fluvoxamine),
114
,
334
,
487

Lynge, Sara,
215

Macartney-Snape, Sue,
468

McCance-Katz, Elinore,
220

McCarran-Ferguson Act,
376
,
493

McCauley, Elizabeth,
446

McClure, James, Jr.,
471
–72

McCurtiss, Henry,
107

McDowell, David,
22
,
218
,
220
,
228
,
230
,
233
,
238
,
429
,
453
,
466

McGuinness, Melvin,
62
,
102

McGuire, Michael,
401
–2,
406
,
407
,
419

MacLean, Paul,
414

Madras, Bertha,
222
–23

Mad Travelers
(Hacking),
194

magnesium,
138

magnetic therapy,
139
,
418

Malaurie, Jean,
213
,
465

managed care,
see
health maintenance organizations

Mandelstam, Nadezhda,
281

Mandelstam, Osip,
281

manic-depressive (bipolar) disorder,
92
–98,
125
–29,
437

antidepressant treatment of,
48
,
106
,
118
,
453

bipolar-two variety of,
92

genetic predisposition to,
48
,
448

initial scientific acceptance of,
319

mixed states in,
48

mood spectrum of,
93

onset of,
25

permanent medication needed in,
126
–27

among prison population,
394

SAMe as mania trigger in,
148

sense of coherent self within,
128
–29

suicide rates of,
248
,
252
,
255

U.S. statistics on,
25

Mann, John,
253
,
473

Manning, Martha,
121
–23,
435
,
440
,
445
,
454

MAOIs,
see
monoamine oxidase inhibitors

Marcus, Eric,
459

marijuana,
224
,
229
–30,
238

Marlowe, Ann,
238

marriage:

mental disorder as stress on,
94
–95

modern choice of partner in,
408

Mason, Paul Bailey,
367
–68

Massachusetts General Hospital, psychosurgery performed at,
164

massage treatments,
137
,
141
–42

maternal interactions, cause/effect linkage demonstrated in,
350

maternal separation,
113
,
183
,
254
,
257
,
452
,
474

Mather, Cotton,
313

Mather, Lydia,
313

Maudsley, Henry,
322
,
485
–86

MDMA (ectasy),
222
,
232
–34,
235